Janumet (Sitagliptin Metformin HCL) / Januvia (Sitagliptin Phosphate)

Janumet (Sitagliptin Metformin HCL) / Januvia (Sitagliptin Phosphate) :-

Januvia tablets 100mg are used to treat Type 2 Diabetes Mellitus (T2DM), also known as non-insulin-dependent diabetes. T2DM is a disease characterised by high blood sugar levels that are difficult to control (poor glycaemic control) due to chronic damage to the beta cells of the pancreas and loss of their normal function, which is the production of insulin in response to increase in blood glucose, such as following a meal. Insulin resistance is another reason for poor glycaemic control in T2DM. Januvia tablets 100mg are an oral antihyperglycaemic medication that helps bring down high blood sugar levels, particularly after a meal, keeps blood sugar levels down between meals and reduces the amount of sugar made in the liver. Januvia tablets 100mg can be used as monotherapy in combination with improved diet and increased exercise or when diet and exercise alone does not provide adequate glycaemic control. Januvia 100 is also used as add-on therapy in combination with other oral antihyperglycaemic medications like metformin, a thiazolidinedione or a sulphonylurea, when diet and exercise, plus one of these other drugs does not provide adequate glycaemic control; also in combination with two other drugs if dual therapy does not provide adequate glycaemic control. Januvia 100 helps restore glycaemic control and helps prevent or delay the development of serious complications of T2DM. These include cardiovascular disease leading to heart attack and stroke. Also microvascular damage (damage to capillaries) in the eye, kidney or nerves can lead to diabetic retinopathy, nephropathy or neuropathy, which contributes to blindness, kidney disease, foot ulcers. In extreme cases microvascular damage can result in amputation.

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